Assay Validation for KIM-1: human urinary renal dysfunction biomarker

Assay Validation for KIM-1: human urinary renal dysfunction biomarker

Urinary kidney injury molecule (KIM-1) is a sensitive quantitative biomarker for early detection of kidney tubular injury. The objective of the present work was to analytically validate this urinary renal injury biomarker. Duo-set reagents from R&D were used to develop the ELISA and validate the assay's linearity, intra-run precision, inter-run precision, lower limit of quantification, recovery...

Kidney Injury Molecule -1 (Kim-1): A Tissue and Urinary Biomarker for Nephrotoxicant-Induced Renal Injury

Urinary KIM-1: a novel biomarker for evaluation of occupational exposure to lead

Chronic occult lead poisoning often develops ensuing occupational lead exposure. Early diagnosis of lead poisoning is critical for timely discontinuation of lead exposure and for prognosis. This study explored the value of urinary kidney injury molecule-1 (KIM-1) in diagnosing renal injury induced by lead at an early stage. We retrospectively analyzed 92 workers exposed to occupational lead and...

Kidney injury molecule-1 (KIM-1): a urinary biomarker and much more.

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Renal Autotransplantation for Urinary Undiversion

Urinary dh ersion has been performed in the past in many patients for different indications. In many of these patients urine can be undiverted to its natural path (urinary undiversion) using new techniques. The most common type of urinary dhersions are: Ileal condiut, ureterosigmoidostomy, cutaneous ureterostomy and nephrostomy. There have been many different methods reported for urinary undive...